In its most recent electronic publication, the Society for Laboratory Automation and Screening (SLAS) features an article on drug repurposing. Therein is discussed the current state of the science as well as present and future challenges. Among the expert panel is Biopra’s Mathieu Arcand, co-chair of the SLAS Drug repurposing special interest group. Read the
Drug repurposing SLAS and Biopra
The past weeks have been abundanly punctuated with high caliber scientific articles describing novel uses for AlphaScreen or AlphaLISA. In the coming weeks we will be commenting some of them either through our News section or via the Alpha technologies users LinkedIn group. You are welcome to join the the discussion.
The National Institues of Health (NIH) announced an unprecented partnership with numerous major pharmaceutical companies along with non-profit organizations in order to speed up drug discovery. Drug discovery efforts have proven incresingly difficult too few successes despite currently available information and technologies. The NIH director Francis Collins hopes that the Accelerating Medicines Partnership (AMP) will
May Biopra be your discovery partner in this new year that holds the promise of new findings. Meanwhile enjoy Google poetry for this new page before us. Cheers! -The Biopra team
Two-time Nobel prize winner Fred Sanger leaves immense heritage including sequencing method. See 13 min interview from NobelPrize.org
Inviting you to join the community for many stimulating discussions. See LinkedIn group.
Nathalie Rouleau and Stéphane Parent from Biopra co-author this article just published in Assay and Drug Development Technologies. It describes a cellular assay with integrated measurements for GPCR activation by a RTK. See Publisher page and Biopra scientific publications.
Multiplexing AlphaScreen and AlphaLISA signals was originally described by Biopra founder Mathieu Arcand in 2010. A recently published study in PLoS ONE uses the same approach to identify small-molecule modifiers of SH2-mediated STAT interactions. This exemplifies one of many potential applications to multiplexing Alpha signals.
Cell publishes a free review on epigenetics and epigenomics tools, approaches and future challenges. Online full text | pdf
Biopra along with the kinase and canadian scientific community regrets the passing of Tony Pawson and invites to continue his legacy (see embedded video).